Abstract: Objective: To study the anti-fatigue effect of brewing bifidobeer. Methods: Mice were randomized into 5 groups;3 groups were given brewing bifidobeer with dosage of 25, 50, 100 ml/kg bw respectively; the blank group was given distilled water at dosage of 50 ml/kg bw and the control group was given ordinary beer with dosage of 50 ml/kg bw. After 30 days, by the loaded swimming test, the death time was observed and recorded; the liver glycogen, serum BUN and LAC were also assayed. Results: High and medium dosage of Brewing bifidobeer can prolong the loaded-swimming time significantly, while decrease the consumption of liver glycogen and the level of BUN and also inhibite the increase of LAC. Conclusion: Brewing bifidobeer has excellent anti-fatigue effect.

Key words: Bifidobacterium, brewing bifidobeer, anti-fatigue, mice