Variation in Geometrical Isomer Composition of Lycopene in Rat Body

Abstract

Abstract: Objective:This study aimed at investigation into variation in geometrical isomer composition of natural lycopene in absorption, transportation and storage in rat body Method: Experimentally, after a single gastric administration of nature lycopene extract, the feces, the wall tissues of small intestine, serum and liver of male SD rats were collected. Total carotenoid fraction was extracted from those and detected by C30-HPLC-PDA. Results: Data of HPLC anaiysis suggested that the isomer composition of lycopene fraction varies drastically during its absorption, transportation and storage in rat body. The total amount of Z-isomers increases significantly. It was proved that this change takes place in serum. This result shows an importance in study on lycopene metabolism in vivo.

Key words: lycopene, geometrical isomerisation, metabolism

LI Jing, HUI Bo-Di. Variation in Geometrical Isomer Composition of Lycopene in Rat Body[J]. FOOD SCIENCE, 2008, 29(9): 591-594.

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Variation in Geometrical Isomer Composition of Lycopene in Rat Body

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