Abstract: The objective of the current research was to develop a resin adsorption method to purify polysaccharides from Acanthopanax sessiliflorus Seem fruits. A comparison of resin adsorption with traditional purification methods was carried out, and the results showed that resin adsorption was the best method. The selected macroporous adsorption resins, HPD-600 and polyamide, were compared for their adsorption and desorption characteristics towards polysaccharides from Acanthopanax sessiliflorus Seem fruits. The deproteinization rate, decolorization rate and polysaccharide loss rate obtained from HPD-600 purification were 66.7%, 82.1% and 29.8%, respectively, and a deproteinization rate of 75.6%, a decolorization rate of 88.1% and a polysaccharide loss rate of 33.7% were obtained using polyamide for polysaccharide purification.

Key words: Acanthopanax sessiliflorus Seem, polysaccharide, purification, macroporous resin