Abstract: In this expeniment the hypoglycemic effects of polysaccharide from moso bamboo leaves (PMBL) on diabetic mice with high blood sugar induced by alloxane were investigated. Fifty diabetic mice were randomly divided into high dosage of PMBL, middle dosage of PMBL, low dosage of PMBL, positive pharmaceutical control group and diabetic model group, and ten general mice were divided as normal control group. Then these groups mice were administered with different dosages PMBL, glybenclamide and physiologic saline, respectively. Feeding, drinking and mouse body weight were recorded. During the experiment, the serum glucose content was determined and the changes of the serum glucose were compared. The results showed that PMBL has a good hypoglycemic effect on alloxan diabetic mice and it can significantly reduce water and food intake and alleviate the weight loss of diabetic mice. Further study results showed that blood glucose of the high-dose-normal mice don’t change significantly.

Key words: leaves of moso bamboo, polysaccharide, alloxane, diabetic, hypoglycemic effect