食品科学 ›› 2019, Vol. 40 ›› Issue (11): 254-260.doi: 10.7506/spkx1002-6630-20180429-385

• 专题论述 • 上一篇    下一篇

植物多糖降血糖作用及机制研究进展

肖瑞希,陈华国,周 欣*   

  1. 贵州师范大学 贵州省山地环境信息系统与生态环境保护重点实验室,贵州省药物质量控制及评价技术工程实验室,天然药物质量控制中心,贵州 贵阳 550001
  • 出版日期:2019-06-15 发布日期:2019-06-28
  • 基金资助:
    国家自然科学基金面上项目(31570358);贵州省高层次创新人才培养项目(黔科合人才(2015)4033号);贵州省优秀青年科技人才项目(黔科合人才[2017]5625);贵州省教育厅青年科技人才成长项目(黔教合KY字[2017]123);贵州省科技计划项目(黔科合支撑[2018]2826)

Recent Progress in Understanding of Hypoglycemic Effect and Underlying Mechanism of Plant Polysaccharides

XIAO Ruixi, CHEN Huaguo, ZHOU Xin*   

  1. Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang 550001, China
  • Online:2019-06-15 Published:2019-06-28

摘要: 糖尿病是高血糖的临床表现之一,长期罹患糖尿病易引发各种并发症。目前尚未发现彻底根治糖尿病的方法,主要采用西药治疗;但是西药具有较严重的副作用,因此,有效降血糖、低毒、副作用小的天然物质备受关注。研究发现,广泛分布于自然界的植物多糖具有良好的降血糖功效,是一类天然的生物活性物质,具有低毒、副作用小的特点,其已成为医药界及保健食品领域的研究热点。本文主要概括了近几年国内外研究的降血糖植物多糖的种类及其降血糖机制。

关键词: 植物多糖, 糖尿病, 降血糖作用, 作用机制

Abstract: Diabetes is one of the clinical manifestations of hyperglycemia, and various complications may be caused by long-term diabetes. At present, no therapy has been found to cure diabetes and the treatment of this disease using western medicine is prevalent. However, western medicine has serious side effects. For this reason, natural substances with high potential to lower blood glucose, low toxicity and few side effects have gained much attention. Plant polysaccharides, widely distributed in nature, have been reported for their good hypoglycemic effect. As natural bioactive substances, they have the characteristics of low toxicity and small side effects making them a research hotspot in the fields of medicinal and health foods. The types of plant polysaccharides with hypoglycemic effects that have been researched worldwide in recent years and the underlying mechanisms are summarized in this article.

Key words: plant polysaccharides, diabetes, hypoglycemic effect, mechanism

中图分类号: