Effect of LSPC on S180 Sarcoma and Immune Function in Mice

Abstract

Abstract: Objective: To discuss the effects of proanthocyanidins from Lotus seedpod (LSPC)on S180 sarcoma and the immune function in mice. Methods: The inhibitory function of LSPC to S180 sarcoma was studied by weighing method, and the effect of LSPC on the immune function in mice was studied through determining carbon granule clearance ability, delayed type hypersen- sitivity (DTH) induced by DNFB and hemolysin production level. Results: LSPC could inhibit the growth of S180 sarcoma in mice, increase the growth index of immune organs, significantly enhance the phagocytosis function of peritoneal macrophage (PMΦ), intensify DTH caused by DNFB, and increase production of antibody. Conclusion: It was primarily proved that LSPC could intensify the immune function in S180 sarcoma-bearing mice and inhibit the mice S180 sarcoma.

Key words: Lotus seedpod procyanidins(LSPC), immune, inhibitory, S180 sarcoma

ZHANG Hai-Hui, DUAN Yu-Qing, DENG Qian-Chun, YANG 尔Ning, XIE Bi-Jun. Effect of LSPC on S180 Sarcoma and Immune Function in Mice[J]. FOOD SCIENCE, 2005, 26(11): 220-223.

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Effect of LSPC on S180 Sarcoma and Immune Function in Mice

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