Study on Molecule Mechanism of Immunoregulation to Spleen Cells of Rat with Flavonoids from Bamboo Leaves

Abstract

Abstract: Objective:Study on immunoregulation of flavonoids from the leaves(FBL)to spleen cells of rat.Methods:The immunities of FBL to spleen cells of rat were evaluated by means of molecule immunology,modern biology of cells and modern molecular biological technology.Results:FBL could hasten synthesization of DNA and protein of spleen cells of rat within a dosage range,accelerate cell proliferation as well as facilitate mRNA expression,exudation and produce of IFNγ.At the same time,IFNγ could activate NK cells,accelerate differentiation of T cells and B cells and maturation of CTL,and catalyze antibody exudation of B cells on the contrary.Conclusion:FBL could enhance immunoregulation function of rat in special dosage and presented typical dose-effect relationship.

Key words: flavonoids from bamboo leaves (FBL), immunoregulation, molecule mechanism, spleen cells

TANG Hao-Guo, WEI Xiao-Xia, LI Ye, CHEN Zong-Dao, XU Bao-Cheng, XIANG Jin-Le. Study on Molecule Mechanism of Immunoregulation to Spleen Cells of Rat with Flavonoids from Bamboo Leaves[J]. FOOD SCIENCE, 2007, 28(9): 523-526.

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Study on Molecule Mechanism of Immunoregulation to Spleen Cells of Rat with Flavonoids from Bamboo Leaves

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