Abstract: Acanthopanax sessiliflorus ( Rupr. et Maxim.) has been used instead of A.senticosus in northeast region of China, but its active components have not been very clear. In this article, the constituents of polyose from A.sessiliflorus fruit were studied by HPLC method. The results showed that the polyose is composed of galactose, mannose, fucose, xylose rhamnose, glucasamine, glucuronic acid, galacturonic acid with mainly four homogeneous whose molecular weight are 21800, 147000, 45400, 18100 respectively. Among them, the monosacchrides of homogeneous polyose-1 I are Gal and Rha in the molar ratio of 1:0.7, whose molecular weight is 18100. The biological activities experiments showed that polyose has certain capability on scavenging hydroxyl radical and increasing the survival time of mice under hypoxia and loaded swimming condition and also increasing the immune activity of mice.

Key words: Acanthopanax sessiliflorus ( Rupr. et Maxim.), polysaccharide