FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (6): 392-394.

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Study on Immunological Activity of Coarse Polysaccharides from Ethanol-insoluble Residue of Schisandra

 YANG  Liu-Qing, CHEN  Rong-Hua, WU  Xiang-Yang, FAN  Qun-Yan, ZHAO  Jiang-Li   

  1. 1. College of Pharmacy, Jiangsu University, Zhenjiang 212013, China; 2. College of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; 3. College of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China
  • Online:2008-06-15 Published:2011-08-26

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Abstract: Objective: To investigate effects of coarse polysaccharides from the ethanol-insoluble residue of Schisandra (CPES) on immunological activtiy of mouse. Method: CPES was extracted with hot-water. Cyclophosphamide (CTX) was uesed to set up the low immunity mice model, and the effects of CPES on phagocytic activity and the level of blood serum hemolysin were studied. Result: B-2 can increase abdominal cavity macrophage phagocytic activity significantly (p<0.001) B-1 can increase abdominal cavity macrophage phagocytic activity (high dose of B-1: p<0.01, low dose of B-1: p<0.05). Only high doses of S. sphenanthera coarse polysaccharides can increase phagocytic activity (phagocytic index p<0.05) and show dose-dependent augmentor effects. CPES can increase the level of mice blood serum hemolysin notably (p<0.01). Conclusion: CPES has potent immunological function.

Key words: ethanol-insoluble residue of Schisandra, coarse polysaccharides, immunological activity