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New regulation mechanisms of natural products and microRNA on metabolic syndrome

  

  • Received:2016-04-21 Revised:2017-03-16 Online:2017-05-15 Published:2017-05-22
  • Contact: guo qin E-mail:guoqin_shiyin@163.com
  • Supported by:
    ;A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)

Abstract: Metabolic syndrome has become a global health problem. microRNA,a short single-stranded endogenously expressed RNA (approximately 22nt) that regulate gene expression at a post-transcriptional level, plays a significant role in the metabolic syndrome. A lot of researches have shown that miRNA plays an important role in the metabolic syndrome. Additionally, diet and dietary supplements can modulate the activities and functions of microRNAs (miRNAs). Recent evidences described in this review highlight the significant role of miRNA in metabolic syndrome and how dietary factors may influence Metabolic syndrome by modulating the activity and function of microRNAs (miRNAs).

Key words: metabolic syndrome, microRNA(miRNA), natural products

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