食品科学 ›› 2023, Vol. 44 ›› Issue (11): 401-409.doi: 10.7506/spkx1002-6630-20220721-247

• 专题论述 • 上一篇    

碳量子点及其荧光探针在食品安全检测应用中的研究进展

杨茂杰,施晓,涂垚,饶钧玥,曹芸榕,吴任之,王利娜,韩国全   

  1. (1.四川农业大学食品学院,食品加工与安全研究所,四川 雅安 625000;2.成都市食品检验研究院,四川 成都 611100)
  • 出版日期:2023-06-15 发布日期:2023-06-30

Research Progress on Carbon Quantum Dots and Their Application as Fluorescent Probes in Food Safety Detection

YANG Maojie, SHI Xiao, TU Yao, RAO Junyue, CAO Yunrong, WU Renzhi, WANG Lina, HAN Guoquan   

  1. (1. Institue of Food Processing and Safety, College of Food Science, Sichuan Agricultural University, Ya’an 625000, China; 2. Chengdu Institute of Food Inspection, Chengdu 611100, China)
  • Online:2023-06-15 Published:2023-06-30

摘要: 合理、有效、快速的食品安全检测方法在保障食品安全方面具有重要意义。碳量子点(carbon quantum dots,CQDs)作为一种新型荧光碳基纳米材料,其表现出较大的斯托克斯位移、良好的光稳定性、可调节的发射波长以及光化学稳定等独特的优点;此外,CQDs具有优良的生物兼容性,其表面经过化学修饰后可与抗体、核酸等大分子偶联而不改变其生物性质,采用CQDs荧光检测技术可提高检测灵敏度、缩短检测时间、降低检测限,节省人力物力。因此,CQDs被认为是传感器研究中功能最强大的碳纳米材料之一。本文综述了碳点的结构、分类和CQDs作为荧光探针的机制,重点介绍了基于CQDs的绿色合成以及作为荧光探针在食品安全检测应用中的研究进展,以期为CQDs的合成和食品安全快速检测技术提供研究思路。

关键词: 绿色合成, 快速检测技术, 病原菌, 重金属, 农药残留, 兽药残留

Abstract: Reasonable, effective and rapid food safety detection methods are of great significance for ensuring food safety. As a new fluorescent carbon based nanomaterial, carbon quantum dots (CQDs) exhibit the advantages of large Stokes shift, good photostability, adjustable emission wavelength and photochemical stability. In addition, CQDs have excellent biocompatibility, and their chemically modified surface can be coupled with antibodies, nucleic acids and other macromolecules without changing their biological properties. The use of CQDs fluorescence detection technology can improve the sensitivity, shorten the detection time, reduce the detection limit, and save human and material resources. Therefore, CQDs can be considered to be one of the most powerful carbon nanomaterials in sensor research. In this paper, the structure, classification and fluorescence mechanism of carbon dots are reviewed, with emphasis on recent progress in green synthesis based on CQDs and the application of CQDs as fluorescent probes in food safety detection, in order to provide new ideas for the synthesis of CQDs and the development of rapid food safety detection technologies.

Key words: green synthesis, rapid detection technologies, pathogenic bacteria, heavy metals, pesticide residues, veterinary residues

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