Research on in vivo Immunostimulation Function of Bifidobacterium Strain BBMN01

Abstract

Abstract: The in vivo immunostimulation function of Bifidobacterium BBMN01 from macrobian were studied in this paper. Mice in the treatment group were perfused by the living bacteria BBMN01in different dose continuously for 3 weeks. The tests for delayed type hypersensitivity(DTH), the peritoneal macrophage phago-function for chicken red blood cells, total hemolytic complement (HC50), and lactic acid dehydrogenase(LDH ) were taken to demonstrated the effect of BBMN01 living bacteria on cell-mediated immune function, humoral immune function, macrophage phagocytosis function and natural killer cell’s activity of mice. In comparison with control group, the lymphocyte trasformation rate, phagocytosis of macrophage and the NK cell’s activity significantly increased in all those treatment group, and the HC50 value of the mice significantly increased in high and medium dose group.

Key words: Bifidobacterium, in vivo, immunostimulation activity

YANG Hai-Ying, LIU Ai-Ping, JIANG Jing-Li, ZHANG Ming, REN Fa-Zheng. Research on in vivo Immunostimulation Function of Bifidobacterium Strain BBMN01[J]. FOOD SCIENCE, 2008, 29(2): 369-372.

[1]	GAO Siwei, ZHANG Jian, ZHANG Qiyue, LI Wenhui, LI He, YU Tian, LIU Xinqi. Preparation and in Vivo Absorption Characteristics of Selenium-Enriched Soybean Peptides [J]. FOOD SCIENCE, 2021, 42(3): 165-172.
[2]	GUAN Jiaqi, LIANG Shengnan, CHEN Qingxue, ZHAO Lina, XIE Qinggang, HUO Guicheng, LI Bailiang. Screening for and Biological Characterization of Bifidobacterium infantis Capable of Promoting Proliferation of Human Fetal Colon Epithelial Cells [J]. FOOD SCIENCE, 2021, 42(18): 86-94.
[3]	CAI Jingjing, XU Xiaoyu, ZHANG Yan, ZHANG Yachuan, WEI Xiaojing, KAN Zeyu, NI Yongqing. Screening for and Antioxidant Activities of High Exopolysaccharide-Producing Bifidobacterium from the Intestinal Tract of Uygur Infants and Their Mothers in Xinjiang [J]. FOOD SCIENCE, 2020, 41(8): 144-151.
[4]	LI Yan, HUANG Wei, LU Mingjian, HU Zhimin, Lü Qiujie. In Vivo Antioxidant Capacity and Flavonoid Composition of the Seeds of Passiflora edulis Sims [J]. FOOD SCIENCE, 2020, 41(1): 203-208.
[5]	FU Linglin, FU Shujie, HUANG Jianjian, QIAN Yi, WANG Chong, WANG Yanbo. Construction of Tropomyosin-Sensitized Mouse Model and Effect of Lactic Acid Bacteria-Induced Intestinal Mucosal Immunity on Allergenicity [J]. FOOD SCIENCE, 2019, 40(7): 169-176.
[6]	WAN Feng, SUN Sirui, HOU Yujia, ZHAO An, ZHANG Sheng, MENG Xiangchen. Comparison of Resistance of Bifidobacterium animalis Strains Isolated from Infants to Simulated Gastrointestinal Stress and Effect of Selected Strain on Activities of Immune Cells in Vitro [J]. FOOD SCIENCE, 2019, 40(22): 118-125.
[7]	WEI Haocheng, SHAO Jie, HE Chuanbo, LI Man, XIONG Hejian. In Vivo Antioxidant Capacity and Immunoenhancing Activity in Mice of Polysaccharides from Abalone Viscera [J]. FOOD SCIENCE, 2018, 39(9): 140-144.
[8]	ZHU Zhenyuan, YU Xiaofeng, JIA Changying, JI Yingping. Optimization of Fermentation Conditions and Anti-Aging Activity in Vivo of Cordyceps militaris?(L.)?Fr.-Fermented Rice [J]. FOOD SCIENCE, 2018, 39(16): 208-213.
[9]	LIU Guorong, LI Xue, WANG Chengtao. Influence of Bifidocin A on the Expression of Whole Cell Proteins in Escherichia coli [J]. FOOD SCIENCE, 2018, 39(14): 85-90.
[10]	LIU Guorong, REN Guimei, LI Xue, WANG Chengtao. Quorum-Sensing Regulation Behavior of Bifidocin A Production in Bifidobacterium animalis [J]. FOOD SCIENCE, 2018, 39(12): 161-166.
[11]	LIU Lu, ZHANG Yan, CHI Jianwei, WEI Zhencheng, ZHANG Mingwei. Promoting Effects of Oligosaccharides from Chinese Yam on the Growth of Two Species of Bifidobacteria in Vitro [J]. FOOD SCIENCE, 2017, 38(6): 130-135.
[12]	ZHANG Qiuxue, LIU Xiaochan, ZHU Zongtao, WAN Feng, SUN Sirui, JIA Fangfang, MENG Xiangchen. Isolation and Diversity Analysis of Bifidobacterium longum from Infant Faeces [J]. FOOD SCIENCE, 2017, 38(24): 8-14.
[13]	LI Jun, ZHANG Limo, GUI Meng, LIU Lei, GUO Xiufeng, LI Pinglan. Resistance of Bifidobacterium RH to Simulated Gastrointestinal Conditions and Preparation of Microcapsules Containing This Strain [J]. FOOD SCIENCE, 2017, 38(22): 14-21.
[14]	LIU Guorong, GAO Yakun, WANG Xin, LIU Yujie, CAO Jilin, WANG Chengtao. Antibacterial Activity and Mechanism of Bifidocin A against Staphylococcus aureus [J]. FOOD SCIENCE, 2017, 38(17): 1-7.
[15]	CUI Lingyu, MIN Weihong, LIU Wei, MAO Jing, MIAO Xinyu, LIU Jingsheng. Effect of Juglans mandshurica Maxim Kernel Protein Isolate on Alleviating Physical Fatigue in Mice [J]. FOOD SCIENCE, 2016, 37(9): 203-207.

Research on in vivo Immunostimulation Function of Bifidobacterium Strain BBMN01

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments