食品科学 ›› 2019, Vol. 40 ›› Issue (5): 289-294.doi: 10.7506/spkx1002-6630-20180129-391

• 专题论述 • 上一篇    下一篇

辣椒素酯生理功能及机制研究进展

臧宇凡,秦 虹*   

  1. 中南大学湘雅公共卫生学院,营养与食品卫生学教研室,湖南 长沙 410078
  • 出版日期:2019-03-15 发布日期:2019-04-02
  • 基金资助:
    国家自然科学基金青年科学基金项目(81302421);湖南省自然科学基金项目(2018JJ2550);“十三五”国家重点研发计划重点专项(2017YFC1601600)

Progress in Research on Physiological Functions and Mechanisms of Capsinoids

ZANG Yufan, QIN Hong*   

  1. Department of Nutrition Science and Food Hygiene, Xiangya School of Public Health, Central South University, Changsha 410078, China
  • Online:2019-03-15 Published:2019-04-02

摘要: 辣椒素酯是从‘CH-19 Sweet’甜椒中提取的一类无刺激性、低毒性的类辣椒素物质,具有多种生理功能和广泛的应用价值。辣椒素酯在调节糖脂代谢、抗肿瘤、抗炎、增强运动耐力和抗氧化方面的作用及机制是目前的研究热点,其在镇痛、抗过敏、增强吞咽反射、上调皮肤胰岛素样生长因子水平以及激活脑区等方面的生物活性也受到关注。本文综述了近年来辣椒素酯的生理功能及作用机制的研究进展,旨在为进一步开发利用辣椒素酯提供理论依据。

关键词: 辣椒素酯, 生理功能, 作用机制, 应用

Abstract: Capsinoids are a class of non-pungent and lowly toxic capsaicin analogs extracted from ‘CH-19 sweet’ pepper and exert various physiological functions, thus having great potential for broad applications. Recently, capsinoids have been studied widely for their benefits in improving lipid and glucose metabolism and promoting anti-tumor, anti-inflammatory and antioxidant functions as well as enhancing endurance exercise capacity. In addition, capsinoids have many other bioactivities including anti-nociceptive, anti-allergic, swallowing reflex-enhancing, dermal insulin-like growth factor-up-regulating and brain region-activating effects. This paper reviews recent studies on capsinoids from physiological and mechanistic viewpoints with the goal of providing a theoretical basis for further studies and applications of these phytochemicals.

Key words: capsinoids, physiological function, mechanism, application

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