FOOD SCIENCE ›› 2003, Vol. 24 ›› Issue (3): 114-117.

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Isolation of Lycium Barbarum Polysaccharide and Its De-fatting Effects on Monosodium Gluta mate Induced Obesity in Female Mice

华中农业大学食品科技系   

  • Online:2003-03-15 Published:2011-12-13

Abstract: In this paper,LBP -4was extracted an d isolated.Then the defatting effec ts of LBP -4on monosodium glutamate induced obesity of mice were investigated.LBP -4w as applied to monosodium glutamate induced obesity of female mice at the dose of 20?40?60mg /(kg•d)for 30days ,respec-tively.Then the body weight,Lee’ s index,fatindex,lipidinserum,th e volume of fat cell and the content of Acc mRNA in fat tissue,but the high dose of LBP -4could decrease it.The r esults showed that LBP -4couldadjust the content of Acc in fat tissue of female mice and could decrease fat in monosodium glutamate induced obesity of female mice’ s body.

Key words: lycium barbarum polysaccharide, ob esity, acetyl -Co A carboxylase, gen e express